New Poster: Integration of Liposomes as a new detection particle into a test strip format and evaluation of its performance character
Lateral Flow Assay (LFA) based point of care (POC) devices are rapidly growing strategies for qualitative and quantitative analysis.
A big advantage over other detection tests are the short time till the result is visible (<30 min) and the low costs As detection particle liposomes were established and compared to usually used colloidal gold particles.
The major difference of liposomes compared to colloidal gold is, that liposomes consist of a phospholipid bilayer forming a hollow space, where aqueous solution can be encapsulated.
Different detection methods can be applied by encapsulating (1) varying concentrations of sulforhodamine B (SRB) (colorimetric and fluorescent) or (2) m-caboxy luminol (chemiluminescent).
The aim of this work was to improve sensitivity with different detection methods of liposomes and the implementation of a successful drying method including stability studies.
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