The Endotoxin-Service announces the successful participation on the LAL PTP study B18.

With this result we can look back on 5 years of successful LAL PTP studies.

We are proud to announce that we now offer an exciting immunoassay platform to our customers that opens up new horizons in biomarker analysis. As one of the very first in Europe we have introduced the benchtop Simoa™ Quanterix SR-X™ Biomarker Detection System.

Simoa™ is a single molecule digital detection technology that represents a platform for multiplexed detection of up to 6 biomarkers per sample. It provides ultra-sensitive detection capabilities, while it remains just as affordable as a regular ELISA assay. Additionally, low volume requirements conserve precious samples. The SR-X™ traps and isolates individual immunocomplexes on paramagnetic beads in thousands of femtoliter-sized wells on a disposable disc. Only one single molecule is needed to obtain a suitable fluorescence signal.

Not only does Quanterix offer over 70 commercially available Simoa kits, the SR-X™ also enables fast assay development tailored to our customers’ demands for both circulating proteins and nucleic acids from blood, without complex pre-analytical extraction and PCR. Customers can rely on our extensive expertise in the development of bead-based assays.

Thus, no matter whether you desire exploratory routine sample measurements or seek to develop novel assays of great efficiency, we can offer the implementation of a vast variety of large molecule assays on Simoa™ technology. The SR-X™ enables us to detect biomarkers with an unparalleled sensitivity, 1000x higher than standard immunoassay methods with high precision across a range of sample types and according to highest quality standards.

Press release: pLDH recombinant panels for malaria diagnostic tests

Microcoat and the Foundation for Innovative New Diagnostics (FIND) announce the launch of pLDH recombinant panels for assessment of the malaria rapid diagnostic test performance in product evaluation and lot testing programs.

Read the full press release here:

Microcoat-FIND_press release_launch rec panels

Find out more about the products here.

Press release: HRP2 recombinant panel now available for malaria rapid diagnostic tests

Microcoat and the Foundation for Innovative New Diagnostics (FIND) announce the launch of HRP2 recombinant panel for assessment of the malaria rapid diagnostic test performance in product evaluation and lot testing programs

Read the full press release here:

Microcoat-FIND_press release_04.09.2017-final

Microcoat expands its technological portfolio by Meso Scale Discovery´s Electrochemiluminescence (MSD-ECL) platform. Based on non-radioactive electrochemiluminescent labels for ultra-sensitive detection, MSD yields higher sensitivity and broader dynamic range compared to ELISA technology. Microcoat offers development of assays from the scratch as well as transfer of classical ELISA formats in addition to method comparison, validation and sample measurement.  Customers profit from our year-long experience in custom-fit optimization and manufacturing of antibody conjugates including MSD´s SULFO-Tag®.

Microcoat´s Laboratory Services announces launch of Thermo Scientific™ Watson™ bioanalytical LIMS V. 7.5

For clinical and pre-clinical drug development support, the right LIMS can accelerate sample turnaround, improve operational efficiency and drive quality and compliance.

Microcoat selected Thermo Scientific™ Watson LIMS™, a bioanalytical LIMS installed in 18 of the top 20 global pharmaceutical organizations and widely used in leading biotechnology and contract research organizations worldwide. Watson LIMS™ facilitates efficient study design and data transfer while streamlining assay validation, bioanalysis, instrument interfacing, sample tracking, results reporting and regulatory compliance.

With Watson LIMS™ Version 7.5 we obtained the latest version which also supports assay validation studies. The system is fully validated to meet all relevant requirements for the support of regulated PK and Immunogenicity studies.

All sample management activities will be transferred from existing systems into Watson LIMS to ensure full traceability from sample reception through analysis to long-term storage. Starting from the implementation of microplate readers, we subsequently plan to integrate more technology platforms (MSD^©, Cobas^©, ELLA^©) to further improve and streamline our workflows.

Thermo Scientific™ Watson LIMS™ software is specifically designed and built to support the bioanalytical workflow, allowing to:

• Manage both small and large molecule workflows in a single solution
• Harmonize laboratory processes across all sites
• Ease exchange of information between sponsors and contract labs
• Increase throughput by automating data handling and reporting tasks
• Promote compliance throughout the workflow
• Implement quantitative concentration assays or qualitative immunogenicity assays
• Track study sample history from receipt to disposal
• Comply with SOPs and reduce the risk of non-compliance” (www.thermofisher.com)

Microcoat and the Foundation for Innovative New Diagnostics (FIND) announce the launch of Positive Control Wells for rapid on-site quality assurance of Malaria Rapid Tests.

Read the full press release here:

MC_FIND press release

For more information please read also the following factsheets:

Positive control wells for malaria rapid diagnostic tests – Pilot introduction in Kenya & Tanzania – http://www.finddx.org/wp-content/uploads/2016/09/MALARIA-PCW-pilot-introduction-Summary-29Sep2016.pdf

Positive control wells for quality assurance of malaria RDTs at point of use – http://www.finddx.org/wp-content/uploads/2016/01/20160316_PCW-Factsheet_FINAL.pdf